Extraction of Caffeine from Tea Leaves - 1151 Words

Extraction of Caffeine from Tea Leaves Introduction Caffeine is soluble in boiling water and as a result it is easily extracted from tea bags by steeping in hot water. This process leaves behind the water insoluble portions of the tea bag. However, water extracts more than just caffeine, so a final separation is done with an organic solvent that will dissolve primarily caffeine. The organic solvent used in this experiment is Dichloromethane (CHâ‚‚Clâ‚‚). Dichloromethane is less polar than water and this difference in polarity allows the separation. Extraction of the tea with the Dichloromethane, followed by evaporation of the organic solvent leaves crude caffeine, which on sublimation yields a relatively pure product. Sublimation is†¦show more content†¦On the TLC plate our tea extract traveled almost the same distance as pure caffeine. The Co-spot traveled the exact same distance as the pure caffeine. The Rf values for caffeine and the Co-spot were 0.166. The Rf value of the tea extract was 0.133. The diff erences in the spots could be due to some impurities in the tea extract and differences in concentration of each spot. After the sublimation 0.003g of pure caffeine was scraped from the test tube. The melting point range of the pure caffeine was tested and found to be 237-239 degrees Celsius. The actual melting point of caffeine is 238. Conclusion The results of the TLC plate showed that the tea extract was very close to the sample of pure caffeine. It was slightly off possibly due to impurities that remained in the tea extract. The caffeine weighed in the flask after the liquid-liquid extracted was 0.012g, which was different from the weight of the caffeine obtained after the sublimation. This difference was likely due to impurities in the caffeine before being purified by sublimation. The caffeine that was extracted from the sublimation experiment had a melting point of 237-239 degrees Celsius, which is the same as the reported value for caffeine. The sublimation resulted in having a totally pure extract of caffeine. Questions 1. Why is sodium chloride added to the tea solution beforeShow MoreRelatedUsing Solid Liquid Extraction Of Caffeine From Tea Leaves867 Words   |  4 PagesThe purpose of this experiment was to use solid-liquid extraction to isolate a crude sample of caffeine from tea leaves and then subsequently purify the isolated sample via sublimation. The two solvents used in the extraction were water and dichloromethane. In addition to caffeine, tea leaves also contain other compounds that must be dealt with including cellulose, proteins/pigments, tannins, and saponins. Cellulose is not soluble in water as a result of its high molecular weight and thereby doesRead MoreCaffeine Lab Report769 Words   |  4 Pagesthe experiment caffeine [C8H10N4O2], is based on a series of procedures. Firstly, it is important to examine the structure of caffeine which is an alkaloid. Typically alkaloids are nitrogen based and found in plants, caffeine itself is composed of a purine ring with functiona l groups of a amide, amine and alkene respectively. Furthermore, Caffeine includeds a lone pair on the nitrogen atom asserting several functional properties(Zhao et al. 206). Under examination of the caffeine structure severalRead MoreEffectiveness Of An Extraction Process And Purification Process955 Words   |  4 Pageseffectiveness of an extraction process and purification process by sublimation is observed and used to selectively separate caffeine from teabags. In the first part of the experiment, water soluble materials, including caffeine, within the teabags are extracted into hot water because the solubility of caffeine in water increases as temperature increases. This is due to the concept that increasing kinetic energy through increasing temperature will allow the molecules in the solute to break apart from the intermolecularRead MoreEssay Separation of Benzoic Acid and Acetanilide1243 Words   |  5 PagesReport 13 October 2011 Table of Contents Separation of Benzoic Acid and Acetanilide 3 Extraction and Purification of Caffeine from Tea 4 Extraction of Trimyristin from Nutmeg 5 Conversion of t-butanol to t-butyl chloride 6 Appendix 7 Calculations 8 Literature and Experimental Values of Benzoic Acid and Acetanilide 9 Experimental Caffeine IR 10 Literature Caffeine IR 11 Experimental Trimyristin IR 12 Literature Trimyristin IR 13 Experimental Tert-Read MoreEssay Acid Base Extraction1511 Words   |  7 Pages Acid Base Extraction The purpose of this laboratory assignment was two-fold, first, we were to demonstrate the extraction of acids and bases, finally, determining what unknowns were present. Second, we were to extract caffeine from tea. 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Companies have made billions off the desire for that extra kick. Caffeine is the most widely consumed behaviorally active substance in the world making it one of the world’s most popular drugs. It’s known for the ability to stimulate the brain and central nervous system. The Chemical structure of caffeine is C8H10N4O2. Before the popular use of caffeine one can assume that peop le were sleepier, and less alert. ConsumptionRead MoreEffects Of Caffeine On Our Lives891 Words   |  4 PagesBiology 30 October 2017 Caffeine Caffeine is one of the most consumed substances in the world. The majority of people consume caffeine as part of their everyday lives. It helps us feel â€Å"alive† in the morning, by giving us the energy and focus that we need throughout the day. Caffeine has many benefits, some of which most people do not even know about. For a drug so commonly used, little attention is paid to the dangerous properties of caffeine products. Because caffeine is part of our everyday livesRead MoreUsing The Solid Liquid And Liquid Extraction Techniques For Extract A Strong Acid1613 Words   |  7 Pages Extraction Aleigha Spaulding Joseph Osazee 10-6-15 Abstract: This report presents the percentage recoveries found when using the solid-liquid and liquid-liquid extraction techniques to extract a strong acid, weak acid, base, and neutral compound from a mixture. During the solid-liquid section of the experiment, 0.5 M NaHCO , 0.5 M NaOH, 0.5 M HCl, and distilled water are used to dissolve and separate the acid, phenol, and amine solutions from the mixture, leaving the neutralRead MoreIsolation of Caffeine from Tea Leaves1831 Words   |  8 PagesIsolation of Caffeine from Tea Leaves Introduction Caffeine is a member of the class of compounds organic chemists call alkaloids. Alkaloids are nitrogencontaining basic compounds that are found in plants. They usually taste bitter and often are physiologically active in humans. The names of some of these compounds are familiar to you even if the structures aren’t: nicotine, morphine, strychnine, and cocaine. The role or roles these compounds play in the life of the plants in which they are found

Article Review Politics And The Policymaking Process

A. Main Theme of Article a. The main theme of the article entitled, â€Å"Politics and the Policymaking Process† is to examine and explain the phases of the policymaking process and identity the theoretical aspects associated with policymaking, as well as, acknowledge the lead contributors in decision making and funding public policies. The article deciphers the policymaking process while identifying the policy problems and the contributors that influence change in public policy. The scholars that contributed to the article, identified five steps in the policymaking process; (1) Identifying policy problems, (2) Formulating policy proposals, (3) Legitimizing public policy, (4) Implementing public policy, and (5) Evaluating public policy. In order to identify policy problems, one must identify the problem’s causes and effects and pinpoint those that contribute to the problem and those that develop solutions to solve those problems. To formulate, legitimize, implement, and evaluate policy proposa ls one must first, identify the first step in the policymaking process. The article concludes with how policies are funded through federal taxes and governmental actions and decisions. B. Summary a. In the beginning of the article, â€Å"Politics and the Policymaking Process†, the author introduces us to the five steps that have been considered the foundation of the policymaking process. 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Auditing Management Expressions of Confidence

Question: Discuss about the case study Auditing for Management Expressions of Confidence. Answer: Introduction: 1. Accounting has been an essential element of finance since the ancient times. In the historic times accountants used to be called as bookkeepers who maintained the records of accounting transactions. However, with the constant development in the process of accounting, it has become professionally certified since the 19th century. There has been development in accounting in many different ways that upgrades the nature of accounting, regulatory system, accounting standards and principles. Accounting is a set of records and recognition of financial transactions that helps in analysis of the performance of the organization or individual in an accounting or financial year. Accounting helps in assessment in assessment of profit and loss in a financial year as well as determines the value of assets and liabilities at the end of the accounting year (Mohammadi, 2015). Though the basic concept of accounting has remained same since the ancient times, the methods, principles and standards have been developing for preparation of accounting statements. Preparation and recording of accounting transactions manually have been developed to that in a computerized manner. Several accounting software have been invented and updated over the period to make the process of recording transactions easy and accurate. Apart from that, conventional method developed to modern accounting method so that the desired results are more accurate. For example, computation of depreciation involved historical value of assets under the conventional method of accounting. But in case of modern accounting method, recent value of asset is considered that produces accurate and fair depreciation charges. In order to keep pace with the recent economic trend, accounting principles and standards are being developed to provide transparent and accurate results. Like standard on recording fo reign exchange transaction according to the closing exchange rate on the recording day provides accurate profit and loss on foreign exchange deals (Soh, Leung Leong, 2015). Similarly, auditing has also been developed over the period to serve the users more efficiently and effectively. It is an organized form of scrutiny and verification of accounting records and statements to evaluate the authenticity of the same. Auditing is a concept, which is formed on the basis of accounting and revolves around the concept of examination of books of accounts and statements. Auditing is conducted to examine whether these statements and records depict a true and fair image of an organizations books of accounts. Just like the accounting information, methods and standards that regulates the process of auditing also been developed from time to time. The accounting and auditing boards have specified the limits of capital and turnover of the assessees exceeding which requires mandatory auditing (Ezzamel Xiao, 2015). Auditing is conducted for both companies and individual assessees depending on their value of turnover. In case of companies, different types of auditing are considered as required by the Corporation laws and auditing standards. For example, internal audit, periodical audit, tax audit, bank audit, forensic audit and many more so that the users of the financial statement can get true picture of the companys performance (Westermann, Bedard Earley, 2015). Auditor is required to provide an opinion on the correctness and fairness of the financial statements through qualified, unqualified and adverse report. The process and requirements of stating such opinions and conclusions have been developed over the period so that it depicts a clear picture (Klychova et al., 2015). As provided in the case of Whigarian view of history, it is true that continuous process of any act with a positive belief always generates progressive and developed results. Similarly, in accounting and auditing constant development and advancement has been made to serve the society in a better and fair way. Such advancement in both the components of finance has been made with respect to save the time in preparing the accounting statements without any error. Such advancement also helps to maintain the necessary records of accounting as well as of auditing in more concise manner. As the education system and industries in economy are increasing at high percentage, it is very important to develop the systems of managing the organizations that presents clear, unambiguous, accurate and authenticated information. At the same time recognition and measuring turnover, profits, losses, expected returns and other required information should not be time consuming (Bedford Ziegler, 2016). Therefore, it is important to develop the systems of different areas of finance that helps in analyzing the financial position and other relevant information. Accountants and auditors have to be keen on learning and practice the new, developed and advanced areas and techniques so that they can serve the company and society in the best possible manner (Soh, Leung Leong, 2015). 2. Many nations have institutionalized the regulations and standards that govern the system of auditing under which auditor independence has become difficult. Auditors perform their work through analytical procedures to provide a conclusion for their clients business. However, some conflicts of interests occur among the professionals while performing their several jobs to serve one objective. In this regard, many authors have provided theories on moral seduction as well as strategic issue cycle. While some of the theories like Sarbanes Oxley Act does not reflect the true picture on independence of the professionals or auditors that is a consequence of incorrect understanding for the biasness of the auditors (Berman et al., 2015). In presenting the opinion on auditing for the clients, the auditors have to be unbiased to perform their audit work. This is because auditing is conducted to provide reliability and authenticity of the books of accounts and financial statements of the organization. Hence, auditors need to examine the books of accounts independently to provide a reasonable opinion on the correctness and fairness of the accounting information. In delivering the examination and opinion on the books of accounts of the clients, auditors have to present their performance based on the intuition, analytical process, qualitative and quantitative measures. However, in analyzing the books of accounts, auditors have the reasonable responsibility while the absolute responsibility is that of the management of the organization (Guiral et al., 2015). There are several reasons based on structural features that create conflicts of interest between auditor- client relationships that affect the professional judgment of the auditors. The structural features of the profession of the auditors are appointing and removing the auditors by the organizations management. Another feature of the structural issue is undertaking of jobs with the clients. Under the first feature independence of auditors are affected by their appointment terms and conditions. Organizations have the freedom to appoint auditors of their choice based on their set criteria. Such appointment based on the different conditions affect the independence of performance of the auditors. In providing, the opinion of the auditors on the clients financial report might be biased for reasons like fear of being removed from the auditing position, increased audit fees and such other reasons. Such threats and weaknesses on the part of auditors appointment affect the independence on th eir unbiased performance and increase the conflicts of interest with the clients relationships. Besides, individual auditors or audit firms having brand name are perceived to be more independent in performing their audit work and delivering the critical opinion on the financial statements of the organizations (Rupp et al., 2015). In case of second feature, undertaking of jobs with the clients also affects the independence of audit work because of the relationship between auditors and clients. Sometimes, the relationship between them builds a common identity and creates a favorable behavior among the fellow members of the group. Apart from that, auditors perform multiple works for their clients other than the audit work. This multiple work performance affects the efficiency and concentration on reviewing the accounting records and books of accounts to examine its fairness and transparency. Accepting of non-audit works by the auditors are also an essential reasons for conflicts of interest in the client and auditors relationship because of the fear of losing job by the auditors (Asare, Wright Zimbelman, 2015). Most of the nations legislative systems have allowed the interest conflicts that have become common in the recent years. Several theorists have raised the question on why do auditors or clients accepts such policies that create the conflicts in performance of the work as well as providing conclusion on the opinion. Accounting and auditing are the most important components that provide the opinion on the continuity of the organization. Accounting provides the information on the profitability, incomes, expenses, value of assets and liabilities, investments and other vital financial information (Downar, Ernstberger Koch, 2016). On the other hand, auditing provides the authenticity, true and fairness of the books of accounts and financial statements of the company. Auditing stress upon the correctness of the recognition of accounting transactions according to the International Financial Reporting Standards as well as Generally Accepted Accounting Principles. At the same time, process of auditing also takes place following the International Auditing Standards that provides the auditors a proper direction for the better performance (Whittle, Mueller Carter, 2016). Hence, it is important to focus and perform the auditing without compromising on their independence so the users are able to get a clear and true picture of the organization. Stakeholders of the companies should be provided the correct information about the company that helps them in taking better and fair business decisions to achieve the goals (Hoos, Kochetova Kozloski d'Arcy, 2015). 3. Independence is an essential factor every auditor is required to have while performing the auditing work. Management of companies might have interests in showing the accounting records and financial statements that favors the performance of the companies. However, it is the responsibility of the independent auditors to present the audit report free from falsification, unbiased on the analysis of the organizations financial status. An auditor should follow the code of ethics and audit principles and standards to perform the auditing of a company to provide a clear understanding and fair work performance. In order to perform the auditing independently, it is important to have unbiased behavior for the client company and fellow member. In this context, most of the nations have developed the principles and standards of audit performance to regulate the performance of auditors effectively and efficiently (Gold et al., 2015). However, sometimes auditors biased behavior whether knowingly or unknowingly affects the independence of the auditor. Auditors biased performance on the auditing of account statements and financial statements might present the conclusions and results in favor of the client company. But, the same does affect the reliability and competence on the performance of the fellow audit members. Since a financial statement of an organization presents the financial status and performance of business as a whole, it is very important to provide unbiased and credible opinion on the audit reports. Audit reports provide four types of opinion- unqualified opinion, qualified opinion, adverse opinion and disclaimer of opinion that should be form an unbiased appraisal from the companys auditor (Hatfield Mullis, 2015). Unqualified opinion in the auditors report provides a clean opinion on the financial statement of the client company for which the audit was conducted. This type of report is presented when auditor determines each of the accounting records and statements are free from errors, misrepresentation and fraud (Westermann, Bedard Earley, 2015). Qualified opinion is provided when auditors find the account statements free from misrepresentations but do not harmonize with the International Financial Reporting Standards and Generally Accepted Accounting Principles (GAAP) (Westermann, Bedard Earley, 2015). Adverse opinion is presented when the financial statements of a company do not conform with the GAAP as well as it reflects gross misrepresentation of the accounting records. This type of opinion provides a negative impact on the companys financial status and its continuity (Gold et al., 2015). Disclaimer of opinion arises when auditor is not able to perform complete audit procedures to provide accurate report due to certain limitations on the scope from the management (Whittle, Mueller Carter, 2016). Since, auditors opinion on the financial statements of the organization helps the stakeholders to form opinion for various purposes, it is important to give unbiased and fair opinion. Ironic rebound effect is portrays unforeseen problems that emerge when auditors strive to overcome certain thoughts, ideas, beliefs, attitudes while performing the audit procedures. Sometimes auditors being biased towards their clients on forming judgments and opinions on the financial statements of the organization. Such biasness does not reflect the true picture of the companys performance and shows the auditors work against the code of ethics and principles of the audit regulations. Auditing is the examination of books of accounts and financial statements of a company to provide a true and fairness review on the performance of the company. Hence, auditors work in this respect is critical and significant as there are various accounting records that need to be examined by using sampling methods. This method of auditing is based on the probability and random selection. Therefore, ironic rebound effect in case of sampling test may provide false results because the selection should be according to value and number of transactions (Aghazadeh Joe, 2015). In order to form a true and fair opinion on the accounting records of the company the auditor is required to follow the necessary principles and standards that regulate the audit procedures. However, it is not possible to check and verify each of the data, evidence, ledger and documents for the purpose of crosscheck, the auditor should be very careful while selecting the data. Such selection of the data provides the overall opinion on the true and fair view of the organizations performance as well as the transparency in maintain the records. Auditors have to overcome with the rebound effect to provide the credible and clear opinion about the company to serve the stakeholders and other users of financial statements in a better way. The auditor should not form any opinion out of biasness or rebound effect on the companys financial statements that is in favor of the client company (Aghazadeh Joe, 2015). Reference List: Aghazadeh, S., Joe, J. R. (2015). How Management's Expressions of Confidence Influence Auditors Skeptical Response to Management's Explanations.Available at SSRN 2623537. Asare, S. K., Wright, A., Zimbelman, M. F. (2015). Challenges Facing Auditors in Detecting Financial Statement Fraud: Insights from Fraud Investigations.Journal of Forensic Investigative Accounting,7(2). Bedford, N. M., Ziegler, R. E. (2016). The contributions of AC Littleton to accounting thought and practice.Memorial Articles for 20th Century American Accounting Leaders,49, 219. Berman, E. M., Bowman, J. S., West, J. P., Van Wart, M. R. (2015).Human resource management in public service: Paradoxes, processes, and problems. Sage Publications. Downar, B., Ernstberger, J., Koch, C. W. (2016). Reviewing a Friend-The Role of Social Ties in Review Work in Auditing.Available at SSRN 2732480. Ezzamel, M., Xiao, J. Z. (2015). The development of accounting regulations for foreign invested firms in China: The role of Chinese characteristics.Accounting, Organizations and Society,44, 60-84. Gold, A., Klynsmit, P., Wallage, P., Wright, A. (2015). The Impact of Auditor Selection Regime and Audit Committee Appointment Power on Investment Decisions.Available at SSRN 2484415. Guiral, A., Rodgers, W., Ruiz, E., Gonzalo-Angulo, J. A. (2015). Can expertise mitigate auditors unintentional biases?.Journal of International Accounting, Auditing and Taxation,24, 105-117. Hatfield, R. C., Mullis, C. (2015). Negotiations between auditors and their clients regarding adjustments to the financial statements.Business Horizons,58(2), 203-208. Hoos, F., Kochetova Kozloski, N., d'Arcy, A. C. (2015). The Importance of the Chief Audit Executive's Communication: Experimental Evidence on Internal Auditors' Judgments in a Two Masters Setting.International Journal of Auditing,19(3), 166-181. Klychova, G. S., Fakhretdinova, E. N., Klychova, A. S., Antonova, N. V. (2015). Development of accounting and financial reporting for small and medium-sized businesses in accordance with international financial reporting standards.Asian Social Science,11(11), 318. Mohammadi, S. (2015). Full development of the theory of accounting and auditing.International Journal of Accounting and Economics Studies,3(1), 7-9. Rupp, D. E., Wright, P. M., Aryee, S., Luo, Y. (2015). Organizational justice, behavioral ethics, and corporate social responsibility: Finally the three shall merge.Management and Organization Review,11(01), 15-24. Soh, D. S., Leung, P., Leong, S. (2015). The development of integrated reporting and the role of the accounting and auditing profession. InSocial Audit Regulation(pp. 33-57). Springer International Publishing. Westermann, K. D., Bedard, J. C., Earley, C. E. (2015). Learning the Craft of Auditing: A Dynamic View of Auditors' On the Job Learning.Contemporary Accounting Research,32(3), 864-896. Whittle, A., Mueller, F., Carter, C. (2016). The Big Fourin the spotlight: Accountability and professional legitimacy in the UK audit market.Journal of Professions and Organization, jow001.

Outsourcing Model of Drugs Development in The Pharmaceutical Industry

Qusestion: Describe the outsourcing model of drugs development in the pharmaceutical industry? Answer: Introduction In the field of pharmaceuticals, outsourcing can be defined as, the contracting or making a partnership model with a third party for related studies and services. The concept of outsourcing was not new, as it came from the general venture of business firms. In the present context of competitive marker and globalization of services and products, the objectives are linked with long-term goals (Higgins, Rodriguez, 2006, pp.351). In this context, focusing on third party for the services implies two peculiar advantages, viz. (i) do not require any critical strategies; (ii) do not need any special competency or capabilities. Talking particularly about the drug development, the outsourcing can be more or less linked with RD outsourcing and clinical development (jones, 2000, pp.341). Furthermore, before discussing the core concepts of outsourcing the drug development, it is also important to discuss that the term is subjected to be more competitive and challenging, similar to other subjects, such as resource planning, insourcing and marketing. Important considerations The key considerations with respect to outsourcing models of drug development in pharmaceutical industries can be made rebuttal with following points (Govender, 2007): When to make the outsourcing Vendor selection and criteria assumption according to the requirements Not to conflict with the in-house expertise and resources Deciding a cost-effective strategy for making outsourcing Recruitment of patient for making the control and variable studies Matching to the guidelines and policies of local, national and international regulatory and ethical classes Cost-effective strategies for outsourcing of drug models by pharmaceutical companies Some of the key considerations, which are pre-requisite for making the settings and assumptions of outsourcing, are discussed in this context. It is more for the companies to identify the cost-effective strategies as they can help in making the model studies fruitful, both according to organizational objective and cost-effective strategies of organization (Gupta, 2009, pp.219). Cross-checking whether the in-house resources and expertise are sufficient for execution of drug candidate studies and clinical services. To check the resources, with respect to requirement and availability. Identification and assessment with respect to the resource. It is necessary to analyze whether the resources are sufficient and optimal for the execution of the studies. Another important consideration is to analyze and cross check whether the in-house project for the same will be cost-effective. Time is also one of the crucial factors. Hence, the time-effectiveness of the work should also be analyzed. Current outsourcing relationships in pharmaceutical industries It is noteworthy to mention that the present report do not contains the figures of investment and reference of specific pharmaceutical firms. The reason being is the cost and the nature of projects (pilot-scale and major projects) differs according to the stages of drug developments (Kaplan Laing, 2005). The current practices of pharmaceutical firms are: Objective to adopt measurable goals and objectives Ensure the service and cost is beneficial for both the parties Mutual respect and partnership model where both parties can learn from each other Appropriate management system and documentation Tract and measure the performance at every stage of drug development or clinical study phases Involvement of both positive and negative feedback from both the ends Progress review, audit and monitoring of the each and every steps Definite communication skills and utilization of conflict resolution strategies Loyalty, confidentiality and appropriate authorization of the information Conclusive note The financial, scientific and appropriate protocol are the key considerations in the process of outsourcing for the drug development procedure in the pharmaceutical firms. Key benefits associated with the outsourcing process are (Lim, K. 2004, pp.287): Increased value of the stakeholders Competitive advantage Accurate resource management and time effective process Improved and organized focus on the core process Cost reduction Technical and scientific ad-hoc support is available to all quality and type of drug designing process. Increase in the regional and global capabilities Source: Goldman Sachs, PhRMA, EFPIA and authors estimates and analyses A general figure of the outsourcing revenue related information spanning from year 1999 to 2007 can be found from figure 1. It can be noted that the revenue being invested in the outsourcing is being increased in the year wise comparison of the global scenario. The outsourcing services can be linked with computation models (docking, high thoughput screening), cell line studies (various cancer cell line), genetic studies (preparing heat map, knock-out gene), animal model studies (mouse, monkey and other), human trials (volunteers individual and diseased individual) and various other techniques, models and experimental tools needed for the course of drug designing. References: GOVENDER, I. 2007. An analysis of the key drivers, decision making and strategic issues with respect to outsourcing in the SA pharmaceutical manufacturing industry. GUPTA, S., WOODSIDE, A., DUBELAAR, C., BRADMORE, D. 2009. Diffusing knowledge-based core competencies for leveraging innovation strategies: Modelling outsourcing to knowledge process organizations (KPOs) in pharmaceutical networks. Industrial Marketing Management, 38(2), 219-227. HIGGINS, M. J., RODRIGUEZ, D. 2006. The outsourcing of RD through acquisitions in the pharmaceutical industry. Journal of Financial Economics, 80(2), 351-383. JONES, O. 2000. Innovation Management as a Post Modern Phenomenon: The Outsourcing of Pharmaceutical RD. British Journal of Management, 11(4), 341-356. Kaplan, W., Laing, R. (2005). Local production of pharmaceuticals: industrial policy and access to medicines. World Bank HNP discussion paper. LIM, K. 2004. The relationship between research and innovation in the semiconductor and pharmaceutical industries (19811997). Research policy, 33(2), 287-321.

Alexandria Hall Essays - Freudian Psychology, Psychology

Alexandria Hall Brian Lisle PHIL 3500 5 December 2016 Psychoanalytic Theory When Sigmund Freud said, " the first person who hurled an insult instead of a stone was the founder of civilization, " he was highlighting the significance of this moment, as it was an example of one of the first times that anyone denied their primitive urge s for social reasons. This concept of self-denial fascinated Freud; he spent much of his life conducting trials to aid him in studying self-denial and other related phenomena , such as desire, sexuality, consciousness, and free will. He compiled his research to develop psychoanalysis, a clinical practice. This clinical, psychological practice inspired many researchers and philosophers, particularly Jacques Lacan , to branch off of Freud's ideas and eventually develop a new way of looking at literature, the psychoanalytic theory. T hough t his theory is no longer popularly used in modern literary cri ticism, it proves useful in the analyza tion of some of the possible origins of sexism within society. However, before one attempts to embrace this endeavor of determining possible origins of such a complex concept, it is important to gain thorough understanding of both Freud's and Lacan's versions of psychoanalysis. Freud, the father of psychoanalysis, contributed many great ideas that have propelled the advancement of both psychology and philosophy. Perhaps the most influential of these ideas was his theory of the id, the ego, and the superego. An id, according to Freud, is the unconscious, instinctual, primitive part of the psyche. What this means is that the id is a part of all human psychology that motivates the impulsive, animal-like drives that are innately instilled in all people. All of this motivation is entirely unconscious, meaning people are never cognitively aware that they are being driven by the id. Furthermore, the id, unlike the ego and the superego, remains infantile throughout the entirety of a person's life. In other words, it does not grow, change, or become influenced by any external force or ideology. This resilience is because the id is never exposed to the external world and therefore cannot be influenced by any of the experiences a person might encounter. T hus, the id remains untainted by social expectations and can consequently be overly-aspirant, self-seeking, and highly chaotic. To help balance out this chaos, according to Freud, the psych developed a mechanism called the ego which acts as a sort of mediator between the id and the external world. Taking the wishes of the id into consideration, the ego operates on the reality principles which uses logic and reason to achieve the best way of satisfying the desires of the id. However, despite its highly reasonable nature, the ego has no moralistic capacity. In other words, the ego is unaware of what is considered m orally right or wrong; according to the id, anything is right if it somehow satisfies the id's desires. Thus, the ego is concerned with social norms, but not with moralistic expectations of society. The ego must work to fight the strength of the id and guide people to make socially-acceptable decisions. In Freud ' s own words, the ego is " like a man on horseback, who has to hold in check the superior strength of the horse , " the horse, in this case, being the id (FREUD CITATION) . However, if the id is the origin of human instinctual desire and the ego is the logical decision-making part of the psyche, and neither of these take moral obligations into account, then what is responsible for the ethical decision making that people practice in their everyday lives? Freud's answer is something called the superego, which develops in children between the ages of three and five. The superego helps to keep both of id and the ego in control by directing the ego to make decisions that not only fulfill desires but also meet the moral expectations of society. The superego achieves this control through what is called the conscience, not to be confused with conscious. The conscience is the part of the superego that disciplines the ego for making morally poor decisions by inducing feelings of remorse, guilt, and regret. Another aspect of the superego

3 Strong Argumentative Essay Examples, Analyzed

3 Strong Argumentative Essay Examples, Analyzed SAT / ACT Prep Online Guides and Tips Need to defend your opinion on an issue? Argumentative essays are one of the most popular types of essays you’ll write in school. They combine persuasive arguments with fact-based research, and, when done well, can be powerful tools for making someone agree with your point of view. If you’re struggling to write an argumentative essay or just want to learn more about them, seeing examples can be a big help. After giving an overview of this type of essay, we provide three argumentative essay examples. After each essay, we explain in-depth how the essay was structured, what worked, and where the essay could be improved. We end with tips for making your own argumentative essay as strong as possible. What Is an Argumentative Essay? An argumentative essay is an essay that uses evidence and facts to support the claim it’s making. Its purpose is to persuade the reader to agree with the argument being made. A good argumentative essay will use facts and evidence to support the argument, rather than just the author’s thoughts and opinions. For example, say you wanted to write an argumentative essay stating that Charleston, SC is a great destination for families. You couldn’t just say that it’s a great place because you took your family there and enjoyed it. For it to be an argumentative essay, you need to have facts and data to support your argument, such as the number of child-friendly attractions in Charleston, special deals you can get with kids, and surveys of people who visited Charleston as a family and enjoyed it. The first argument is based entirely on feelings, whereas the second is based on evidence that can be proven. The standard five paragraph format is common, but not required, for argumentative essays. These essays typically follow one of two formats: the Toulmin model or the Rogerian model. The Toulmin model is the most common. It begins with an introduction, follows with a thesis/claim, and gives data and evidence to support that claim. This style of essay also includes rebuttals of counterarguments. The Rogerian model analyzes two sides of an argument and reaches a conclusion after weighing the strengths and weaknesses of each. 3 Good Argumentative Essay Examples + Analysis Below are three examples of argumentative essays, written by yours truly in my school days, as well as analysis of what each did well and where it could be improved. Argumentative Essay Example 1 As online learning becomes more common and more and more resources are converted to digital form, some people have suggested that public libraries should be shut down and, in their place, everyone should be given an iPad with an e-reader subscription. Proponents of this idea state that it will save local cities and towns money because libraries are expensive to maintain. They also believe it will encourage more people to read because they won’t have to travel to a library to get a book; they can simply click on what they want to read and read it from wherever they are. They could also access more materials because libraries won’t have to buy physical copies of books; they can simply rent out as many digital copies as they need. However, it would be a serious mistake to replace libraries with tablets. First, digital books and resources are associated with less learning and more problems than print resources. A study done on tablet vs book reading found that people read 20-30% slower on tablets, retain 20% less information, and understand 10% less of what they read compared to people who read the same information in print. Additionally, staring too long at a screen has been shown to cause numerous health problems, including blurred vision, dizziness, dry eyes, headaches, and eye strain, at much higher instances than reading print does. People who use tablets and mobile devices excessively also have a higher incidence of more serious health issues such as fibromyalgia, shoulder and back pain, carpal tunnel syndrome, and muscle strain. I know that whenever I read from my e-reader for too long, my eyes begin to feel tired and my neck hurts. We should not add to these problems by giving people, especially young p eople, more reasons to look at screens. Second, it is incredibly narrow-minded to assume that the only service libraries offer is book lending. Libraries have a multitude of benefits, and many are only available if the library has a physical location. Some of these benefits include acting as a quiet study space, giving people a way to converse with their neighbors, holding classes on a variety of topics, providing jobs, answering patron questions, and keeping the community connected. One neighborhood found that, after a local library instituted community events such as play times for toddlers and parents, job fairs for teenagers, and meeting spaces for senior citizens, over a third of residents reported feeling more connected to their community. Similarly, a Pew survey conducted in 2015 found that nearly two-thirds of American adults feel that closing their local library would have a major impact on their community. People see libraries as a way to connect with others and get their questions answered, benefits tablets canà ¢â‚¬â„¢t offer nearly as well or as easily. While replacing libraries with tablets may seem like a simple solution, it would encourage people to spend even more time looking at digital screens, despite the myriad issues surrounding them. It would also end access to many of the benefits of libraries that people have come to rely on. In many areas, libraries are such an important part of the community network that they could never be replaced by a simple object. Analysis The author begins by giving an overview of the counter-argument, then the thesis appears as the first sentence in the third paragraph. The essay then spends the rest of the paper dismantling the counter argument and showing why readers should believe the other side. What this essay does well: Although it’s a bit unusual to have the thesis appear fairly far into the essay, it works because, once the thesis is stated, the rest of the essay focuses on supporting it since the counter-argument has already been discussed earlier in the paper. This essay includes numerous facts and cites studies to support its case. By having specific data to rely on, the author’s argument is stronger and readers will be more inclined to agree with it. For every argument the other side makes, the author makes sure to refute it and follow up with why her opinion is the stronger one. In order to make a strong argument, it’s important to dismantle the other side, which this essay does this by making the author's view appear stronger. How this essay could be improved: This is a shorter paper, and if it needed to be expanded to meet length requirements, it could include more examples and go more into depth with them, such as by explaining specific cases where people benefited from local libraries. Additionally, while the paper uses lots of data, the author also mentions their own experience with using tablets. This should be removed since argumentative essays focus on facts and data to support an argument, not the author’s own opinion or experiences. Replacing that with more data on health issues associated with screen time would strengthen the essay. Some of the points made aren't completely accurate, particularly the one about digital books being cheaper. It actually often costs a library more money to rent out numerous digital copies of a book compared to buying a single physical copy. Make sure in your own essay you thoroughly research each of the points and rebuttals you make, otherwise you'll look like you don't know the issue that well. Argumentative Essay Example 2 Malaria is an infectious disease caused by parasites that are transmitted to people through female Anopheles mosquitoes. Each year, over half a billion people will become infected with malaria, with roughly 80% of them living in Sub-Saharan Africa. Nearly half a million people die of malaria every year, most of them young children under the age of five. Unlike many other infectious diseases, the death toll for malaria is rising. While there have been many programs designed to improve access to malaria treatment, the best way to reduce the impact of malaria in Sub-Saharan Africa is to focus on reducing the number of people who contract the disease in the first place, rather than waiting to treat the disease after the person is already infected. There are multiple drugs available to treat malaria, and many of them work well and save lives, but malaria eradication programs that focus too much on them and not enough on prevention haven’t seen long-term success in Sub-Saharan Africa. A major program to combat malaria was WHO’s Global Malaria Eradication Programme. Started in 1955, it had a goal of eliminating malaria in Africa within the next ten years. Based upon previously successful programs in Brazil and the United States, the program focused mainly on vector control. This included widely distributing chloroquine and spraying large amounts of DDT. More than one billion dollars was spent trying to abolish malaria. However, the program suffered from many problems and in 1969, WHO was forced to admit that the program had not succeeded in eradicating malaria. The number of people in Sub-Saharan Africa who contracted malaria as well as the number of malaria deaths had actually increased over 10% during the time the program was active. One of the major reasons for the failure of the project was that it set uniform strategies and policies. By failing to consider variations between governments, geography, and infrastructure, the program was not nearly as successful as it could have been. Sub-Saharan Africa has neither the money nor the infrastructure to support such an elaborate program, and it couldn’t be run the way it was meant to. Most African countries don't have the resources to send all their people to doctors and get shots, nor can they afford to clear wetlands or other malaria prone areas. The continent’s spending per person for eradicating malaria was just a quarter of what Brazil spent. Sub-Saharan Africa simply can’t rely on a plan that requires more money, infrastructure, and expertise than they have to spare. Additionally, the widespread use of chloroquine has created drug resistant parasites which are now plaguing Sub-Saharan Africa. Because chloroquine was used widely but inconsistently, mosquitoes developed resistance, and chloroquine is now nearly completely ineffective in Sub-Saharan Africa, with over 95% of mosquitoes resistant to it. As a result, newer, more expensive drugs need to be used to prevent and treat malaria, which further drives up the cost of malaria treatment for a region that can ill afford it. Instead of developing plans to treat malaria after the infection has incurred, programs should focus on preventing infection from occurring in the first place. Not only is this plan cheaper and more effective, reducing the number of people who contract malaria also reduces loss of work/school days which can further bring down the productivity of the region. One of the cheapest and most effective ways of preventing malaria is to implement insecticide-treated bed nets (ITNs). These nets provide a protective barrier around the person or people using them. While untreated bed nets are still helpful, those treated with insecticides are much more useful because they stop mosquitoes from biting people through the nets, and they help reduce mosquito populations in a community, thus helping people who don’t even own bed nets. Bed nets are also very effective because most mosquito bites occur while the person is sleeping, so bed nets would be able to drastically reduce the number of transmissions during the night. In fact, transmission of malaria can be reduced by as much as 90% in areas where the use of ITNs is widespread. Because money is so scarce in Sub-Saharan Africa, the low cost is a great benefit and a major reason why the program is so successful. Bed nets cost roughly 2 USD to make, last several years, and can protect two adults. Studies have shown that, for every 100-1000 more nets are being used, one less child dies of malaria. With an estimated 300 million people in Africa not being protected by mosquito nets, there’s the potential to save three million lives by spending just a few dollars per person. Reducing the number of people who contract malaria would also reduce poverty levels in Africa significantly, thus improving other aspects of society like education levels and the economy. Vector control is more effective than treatment strategies because it means fewer people are getting sick. When fewer people get sick, the working population is stronger as a whole because people are not put out of work from malaria, nor are they caring for sick relatives. Malaria-afflicted families can typically only harvest 40% of the crops that healthy families can harvest. Additionally, a family with members who have malaria spends roughly a quarter of its income treatment, not including the loss of work they also must deal with due to the illness. It’s estimated that malaria costs Africa 12 billion USD in lost income every year. A strong working population creates a stronger economy, which Sub-Saharan Africa is in desperate need of. Analysis This essay begins with an introduction, which ends with the thesis (that malaria eradication plans in Sub-Saharan Africa should focus on prevention rather than treatment). The first part of the essay lays out why the counter argument (treatment rather than prevention) is not as effective, and the second part of the essay focuses on why prevention of malaria is the better path to take. What this essay does well: The thesis appears early, is stated clearly, and is supported throughout the rest of the essay. This makes the argument clear for readers to understand and follow throughout the essay. There’s lots of solid research in this essay, including specific programs that were conducted and how successful they were, as well as specific data mentioned throughout. This evidence helps strengthen the author’s argument. How this essay could be improved: The author makes a case for using expanding bed net use over waiting until malaria occurs and beginning treatment, but not much of a plan is given for how the bed nets would be distributed or how to ensure they’re being used properly. By going more into detail of what she believes should be done, the author would be making a stronger argument. The introduction of the essay does a good job of laying out the seriousness of the problem, but the conclusion is short and abrupt. Expanding it into its own paragraph would give the author a final way to convince readers of her side of the argument. Argumentative Essay Example 3 As college sports continue to be hugely popular and the National Collegiate Athletic Association (NCAA) brings in large amounts of revenue, people have revived the debate on whether college athletes should get paid. There are many ways payments could work. They could be in the form of a free-market approach, where athletes are able to earn whatever the market is willing to pay them, it could be a set amount of money per athlete, or student athletes could earn income from endorsements, autographs, and control of their likeness, similar to the way top Olympians earn money. Proponents of the idea believe that, because college athletes are the ones who are training, participating in games, and bringing in audiences, they should receive some sort of compensation for their work. If there were no college athletes, the NCAA wouldn’t exist, college coaches wouldn’t receive there (sometimes very high) salaries, and brands like Nike couldn’t profit from college sports. In fact, the NCAA brings in roughly $1 billion in revenue a year, but college athletes don’t receive any of that money in the form of a paycheck. Additionally, people who believe college athletes should be paid state that paying college athletes will actually encourage them to remain in college longer and not turn pro as quickly, either by giving them a way to begin earning money in college or requiring them to sign a contract stating they’ll stay at the university for a certain number of years while making an agreed-upon salary. Supporters of this idea point to Zion Williamson, the Duke basketball superstar, who, during his freshman year, sustained a serious knee injury. Many argued that, even if he enjoyed playing for Duke, it wasn’t worth risking another injury and ending his professional career before it even began for a program that wasn’t paying him. Williamson seems to have agreed with them and declared his eligibility for the NCAA draft later that year. If he was being paid, he may have stayed at Duke longer. In fact, roughly a third of student athletes surveyed stated that receiving a salary while in college would make them â€Å"strongly consider† remaining collegiate athletes longer before turning pro. Paying athletes could also stop the recruitment scandals that have plagued the NCAA. In 2018, the NCAA stripped the University of Louisville's men's basketball team of its 2013 national championship title because it was discovered coaches were using sex workers to entice recruits to join the team. There have been dozens of other recruitment scandals where college athletes and recruits have been bribed with anything from having their grades changed, to getting free cars, to being straight out bribed. By paying college athletes and putting their salaries out in the open, the NCAA could end the illegal and underhanded ways some schools and coaches try to entice athletes to join. People who argue against the idea of paying college athletes believe the practice could be disastrous for college sports. By paying athletes, they argue, they’d turn college sports into a bidding war, where only the richest schools could afford top athletes, and the majority of schools would be shut out from developing a talented team (though some argue this already happens because the best players often go to the most established college sports programs, who typically pay their coaches millions of dollars per year). It could also ruin the tight camaraderie of many college teams if players become jealous that certain teammates are making more money than they are. They also argue that paying college athletes actually means only a small fraction would make significant money. Out of the 350 Division I athletic departments, fewer than a dozen earn any money. Nearly all the money the NCAA makes comes from men’s football and basketball, so paying college athletes would make a small group of menwho likely will be signed to pro teams and begin making millions immediately out of collegerich at the expense of other players. Those against paying college athletes also believe that the athletes are receiving enough benefits already. The top athletes already receive scholarships that are worth tens of thousands per year, they receive free food/housing/textbooks, have access to top medical care if they are injured, receive top coaching, get travel perks and free gear, and can use their time in college as a way to capture the attention of professional recruiters. No other college students receive anywhere near as much from their schools. People on this side also point out that, while the NCAA brings in a massive amount of money each year, it is still a non-profit organization. How? Because over 95% of those profits are redistributed to its members’ institutions in the form of scholarships, grants, conferences, support for Division II and Division III teams, and educational programs. Taking away a significant part of that revenue would hurt smaller programs that rely on that money to keep running. While both sides have good points, it’s clear that the negatives of paying college athletes far outweigh the positives. College athletes spend a significant amount of time and energy playing for their school, but they are compensated for it by the scholarships and perks they receive. Adding a salary to that would result in a college athletic system where only a small handful of athletes (those likely to become millionaires in the professional leagues) are paid by a handful of schools who enter bidding wars to recruit them, while the majority of student athletics and college athletic programs suffer or even shut down for lack of money. Continuing to offer the current level of benefits to student athletes makes it possible for as many people to benefit from and enjoy college sports as possible. Analysis This argumentative essay follows the Rogerian model. It discusses each side, first laying out multiple reasons people believe student athletes should be paid, then discussing reasons why the athletes shouldn’t be paid. It ends by stating that college athletes shouldn’t be paid by arguing that paying them would destroy college athletics programs and cause them to have many of the issues professional sports leagues have. What this essay does well: Both sides of the argument are well developed, with multiple reasons why people agree with each side. It allows readers to get a full view of the argument and its nuances. Certain statements on both sides are directly rebuffed in order to show where the strengths and weaknesses of each side lie and give a more complete and sophisticated look at the argument. How this essay could be improved: Using the Rogerian model can be tricky because oftentimes you don’t explicitly state your argument until the end of the paper. Here, the thesis doesn’t appear until the first sentence of the final paragraph. That doesn’t give readers a lot of time to be convinced that your argument is the right one, compared to a paper where the thesis is stated in the beginning and then supported throughout the paper. This paper could be strengthened if the final paragraph was expanded to more fully explain why the author supports the view, or if the paper had made it clearer that paying athletes was the weaker argument throughout. 3 Tips for Writing a Good Argumentative Essay Now that you’ve seen examples of what good argumentative essay samples look like, follow these three tips when crafting your own essay. #1: Make Your Thesis Crystal Clear The thesis is the key to your argumentative essay; if it isn’t clear or readers can’t find it easily, your entire essay will be weak as a result. Always make sure that your thesis statement is easy to find. The typical spot for it is the final sentence of the introduction paragraph, but if it doesn’t fit in that spot for your essay, try to at least put it as the first or last sentence of a different paragraph so it stands out more. Also make sure that your thesis makes clear what side of the argument you’re on. After you’ve written it, it’s a great idea to show your thesis to a couple different peopleclassmates are great for this. Just by reading your thesis they should be able to understand what point you’ll be trying to make with the rest of your essay. #2: Show Why the Other Side Is Weak When writing your essay, you may be tempted to ignore the other side of the argument and just focus on your side, but don’t do this. The best argumentative essays really tear apart the other side to show why readers shouldn’t believe it. Before you begin writing your essay, research what the other side believes, and what their strongest points are. Then, in your essay, be sure to mention each of these and use evidence to explain why they’re incorrect/weak arguments. That’ll make your essay much more effective than if you only focused on your side of the argument. #3: Use Evidence to Support Your Side Remember, an essay can’t be an argumentative essay if it doesn’t support its argument with evidence. For every point you make, make sure you have facts to back it up. Some examples are previous studies done on the topic, surveys of large groups of people, data points, etc. There should be lots of numbers in your argumentative essay that support your side of the argument. This will make your essay much stronger compared to only relying on your own opinions to support your argument. Summary: Argumentative Essay Sample Argumentative essays are persuasive essays that use facts and evidence to support their side of the argument. Most argumentative essays follow either the Toulmin model or the Rogerian model. By reading good argumentative essay examples, you can learn how to develop your essay and provide enough support to make readers agree with your opinion. When writing your essay, remember to always make your thesis clear, show where the other side is weak, and back up your opinion with data and evidence. What's Next? Do you need to write an argumentative essay as well?Check out our guide on the best argumentative essay topics for ideas! You'll probably also need to write research papers for school.We've got you covered with 3 potential topics for research papers. Your college admissions essay may end up being one of the most important essays you write. Follow our step-by-step guide on writing a personal statement to have an essay that'll impress colleges. Have friends who also need help with test prep? Share this article! Tweet Christine Sarikas About the Author Christine graduated from Michigan State University with degrees in Environmental Biology and Geography and received her Master's from Duke University. In high school she scored in the 99th percentile on the SAT and was named a National Merit Finalist. She has taught English and biology in several countries. Get Free Guides to Boost Your SAT/ACT Get FREE EXCLUSIVE insider tips on how to ACE THE SAT/ACT. 100% Privacy. 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Is good communication in the workplace important Essay - 2

Is good communication in the workplace important - Essay Example In the current times of rapid globalization, development of pluralistic society and diverse workforce necessitate cross-cultural understanding. Effective communication helps to overcome the barrier of cultural differences and promotes mutual respect. Consequently, good communication within workforce significantly enhances work productivity. Promoting and creating effective channels of communication within workplace has emerged as critical issue mainly because it helps to disseminate important information across the workforce. Various channels and tools of communication serve as vital linkages for the management and workers to keep abreast of changes within and outside the organizations. Technology has significantly widened the scope of communication and provided people with wide array of communication tools like computer, internet, emails, mobiles, social networking sites etc. The organizational communication thrives on technology-based tools to communicate across workers. The management exploits these tools to inform its workforce about its vision, mission, plans and policies. This helps workers to align their personal and professional goals for achieving organizational goals with higher efficiency. Moreover, effective communication between management and workers empowers workforce with relevant information and equips them with informed choices to make effective decisions. Feedback on work and organizational policies is also important communication strategy within workplace. The feedback system is important way that management exploits in order to encourage workers’ participation in developing strategies and plans for more efficient delivery of organizational goals and objectives. It promotes collective goals and shared learning. The informal chats with employees help management to understand workers’ expectations, ideologies and cultural competencies that can be exploited judiciously for higher personal and